PHOTO: EAST NEWS/SCIENCE PHOTO LIBRARY Illustration of metastatic melanoma cells invading a blood vessel. Cancer cells are here coloured purple. Within them, mitochondria (blue) and a rounded nucleus can be seen. Advancing by out- growths of their cytoplasm (pseudopodia), the melanoma cancer cell at front is penetrating the blood vessel wall. Red blood cells can be seen flowing within the blood vessel. Metastasis is the spread of cancer malignancy from a primary cancer site to another site. The spread can occur through the blood, lymph, or across a body cavity. In this case the primary site of cancer is melanoma of the skin. It is the most serious of skin cancers in which skin pigment cells develop tumours.
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